From your screen to your doorstep
With our state-of-the-art RNA design processes, we develop and assemble DNA templates required for the rapidly evolving RNA technologies, including mRNA, self-amplifying RNA, and circRNA*. From conceptualizing the template to final RNA product, the RFC can deliver through a unique and powerful team that brings expertise in RNA modality design and formulation. Depending on your particular need, one modality may prove more effective than the others. We’re leveraging our expertise and facilities to provide access to any modality.
*research use only, not available for commercial sale
Image: mRNA is the most widely modality; however, self amplifying RNA and circular RNA work through unique mechanisms to offer new approaches to translational drugs.
The right modality
While mRNA is by far the most widely accepted modality, they each bring their own unique advantages and disadvantages. Since selecting the right modality can be difficult, we aim to provide a unique opportunity to easily and simultaneously evaluate each modality. Provide your gene of interest, and we can deliver a multi-modality kit for your team to explore in your context.
Tailoring the fit
The RFC’s Golden Gate Assembly assembly platform bring incredible flexibility for evaluating key principles such as homogenous ends, gene mutations, exploring 5′ or 3′ untranslated regions, or unique poly-A tail structures/lengths. We also have saRNA and circRNA experts that can help design optimization experiments for your application.
Empowering research driving discoveries
The RFC stands as a beacon for researchers seeking to push the boundaries of RNA research. By providing a comprehensive suite of RNA modalities, compatible with nearly any gene imaginable, we empower scientific advancements in translational drug research.